Product Description
Isotretinoin 20 mg
The dose of isotretinoin patients receive is dependent on their weight and the severity of the condition Highdose treatments are administered between 05 mgkgday to 2 mgkgday usually at 05 to 1 mgkgday given as a single dose with food Usually a course will last 810 months A second course may be required Efficacy appears to be related to the cumulative dose of isotretinoin taken with a total cumulative dose over each course of 120150 mgkg used as a guideline
Nearly all patients achieve initial clearing of acne during a normal course of isotretinoin therapy 90 of patients achieve excellent clearance of their acne after a cumulative dose of 150 mgkg
Lowerdosage treatments such as 1020 mgday approxi20 mgmately half the high dosage treatments above can also be effective with greatly diminished side effects However such lower dosage courses may be associated with higher relapse rates requiring additional courses especially if not taken for enough time
Usually a starting dose of 20 mg is taken with the largest meal of the day After a few months the dose is increased eg to 40 mgd If sideeffects permit a higher dose such as 60 mgd can be prescribed although daily dose rarely exceeds 60 mg If 20 mg capsules are supplied patients may take for example 20 mg one day then 40 mg the next to provide an average daily dose of 30 mgd In most cases isotretinoin achieves a complete clearing of acne during a standarddose 1216 week course Some patients acne will respond to a course before recurring needing multiple courses of treatment